Long-limb or Distal Gastric Bypass for Superobesity - Randomized Study

Oslo University Hospital115 enrolled

Overview

The main study objective: To evaluate long-limb gastric bypass (150 cm alimentary limb) vs. "distal" gastric bypass (common channel 150 cm) in the treatment of superobesity (BMI 50-60 kg/m2). The main study hypothesis: Distal bypass accomplish an estimated 10-20 % larger weightloss than long-limb gastric bypass 1 year after surgery. Patients subject to distal bypass have more gastrointestinal side effects and more extensive nutritional deficiences compared to long-limb gastric bypass.

Technical data will later be published in detail

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

115

Conditions

Obesity

Interventions

long-limb gastric bypassPROCEDURE

Laparoscopic long-limb gastric bypass (150 cm alimentary limb, 50 cm biliopancreatic limb)

distal gastric bypassPROCEDURE

Laparoscopic distal gastric bypass (150 cm common channel, 50 cm biliopancreatic limb)

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * BMI 50 - 60 kg/m2 at admission for evaluation for bariatric surgery * BMI 48 - 62 kg/m2 at study inclusion * informed consent * scheduled for bariatric surgery Exclusion Criteria: * previous bariatric surgery * previous major abdominal surgery * previous history or established urolithiasis * viral hepatitis, liver cirrhosis of any kind * factors making the patient not eligible to understand and commit to the study protocol (severe psychiatric disease or drug/narcotic abuse)

Locations (1)

Aker university Hospital, Surgical Dep., The Hospital of Vestfold, Surgical Dep.

Oslo, Norway

Outcomes

Primary Outcomes

Primary outcome: weight loss

physical examination

Time frame: 2 years postoperatively