The efficacy and safety of uterine artery embolization, as compared with standard surgical methods, for the treatment of symptomatic uterine fibroids remain uncertain. The purpose of this trial is to evaluate the uterine volume and tumor size reduction, symptomatic relief, complication, fertility, ovarian function and quality of life with uterine artery embolization for uterine fibroids comparing with standard surgical methods.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
900
Uterine artery embolization will be done for the patients who enroll into UAE group and desire for future pregancy and reserving uterus.Myomectomy will be performed for the patients who enroll into SURGERY group and desire for future pregancy and reserving uterus.Hysterectomy will be done for the patients who enroll into SURGERY group and don't desire for reserving uterus and/or future pregnancy.
Nanfang Hospital of Nanfang medical University
Guangzhou, Guangdong, China
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China
the first Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China
Sun Yat-sen University
Guangzhou, Guangdong, China
quality of life
Time frame: 1,3,5,10 year.
pregnant
Time frame: 3 years
tumor recurrence
Time frame: 1,3,5,10 years
complications
Time frame: 3,6,12,24 months
ovarian functions
Time frame: 3,6,12 months, 2,3,5 and 10 years
symptom relief
Time frame: 3,6,12,24 months
tumour volume
Time frame: 3,6,12 18 24 months and 3,5,10 years
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