Assessment of Treatment With PulseHaler on Patients With Chronic Obstructive Pulmonary Disease (COPD)

Inclusion Criteria: * Diagnosis of COPD * Diagnosis established for at least 1 year; * Post-bronchodilator FEV1/FVC \< 0.7 * Post bronchodilator FEV1 \<70% predicted * Age: 40 years or older * Smoking cigarettes, at least 10PY * Patient signed the informed consent form Exclusion Criteria: * Bullous Emphysema (ruled out by recent CT) * Hospitalization due to exacerbation of COPD within the last 3 months * Upper respiratory infection and/or exacerbation of COPD in the last 4 weeks * Systemic steroid treatment in the last 4 weeks * Women at the age of fertility, who are pregnant, or plan pregnancy, or do not use contraceptive. * Severe cardiac disease, e.g., CHF grade 3 or higher * Acute MI within last 3 months * CABG within last 3 months * Other severe systemic disease