A Trial Comparing a Paclitaxel Eluting Stent With Biodegradable Polymer Versus a Bare Metal Stent

Inclusion Criteria: * Patient signing informed consent after receiving extensive written and oral information about the trial, * Older than 18 years, * Agreement to have a control examination done after six months, * Patients with angina pectoris symptoms (CCS stages i-IV, unstable angina pectoris Braunwald B and C) and patients with documented silent ischemia; * Patients with one or more de novo lesions which all are to be dilated in the same session; * Target vessel diameter of 2.5 to 4.0 mm Exclusion Criteria: * Female patients of child bearing age with pregnancy suspicion(a pregnancy test will be done in this cases) * Acute myocardial infarction (Q wave or non Q wave ) with documented CK levels more than 2 fold higher than the normal values in the preceding 72 hours , * Substantially calcified lesion precluding successful pre dilatation, * Ejection Fraction less than 35%, * Patient with previous PCI with one DES, * Target lesion \< 2.5 mm * Coagulopathy or clotting disorders, leucopenia anemia or thrombocytopenia, * Allergy, hypersensitivity or adverse reaction to paclitaxel, * Intolerance to the clopidogrel, Ticlopidine or Aspirin or unable to receive clopidogrel for one year, * Active duodenal or gastric ulcer, * Life Expectancy less than 1 year, * Patient with LM disease (\>50%)