Safety and Immunogenicity (Non-inferiority) of a Purified Chick Embryo Cell Vaccine Vaccine Administered in Two Different Schedules (Conventional Versus Abbreviated Schedule)

Inclusion Criteria: * Male and female subjects 18-50 years of age who: * are in good health at the time of entry into the study as determined by medical history, physical examination and clinical judgment of the investigator; * volunteer for the simulated post-exposure vaccination courses and blood draws; * have given a written informed consent; informed consent must be obtained for all the subjects before enrolment in the study; * are available for all the visits scheduled in the study. Exclusion Criteria: * Subjects with the below criteria were excluded: * pregnancy or unwillingness to practice acceptable contraception during participation in the study; * a history of rabies immunization; * a significant acute or chronic infectious disease that may impact the subject's safety and /or immunogenicity in the Investigators opinion at the time of enrolment; * fever ≥ 38.0°C (axillary) or/and significant acute or chronic infection requiring systemic antibiotic or antiviral therapy within the past 7 days before enrolment; * treatment with corticosteroids, immunosuppressive or antimalaria drugs during the two month period before enrolment; * administration of any vaccine within the past 14 days before enrolment; * known/suspected immunodeficiency, or autoimmune disease, or any immunologic disorder; * history of allergy to egg protein; * known hypersensitivity to neomycin, tetracycline, amphotericin-B, or any other vaccine component; * treatment with parenteral immunoglobulin preparation, blood products, and/or plasma derivatives within the past 3 months; * mental condition rendering the subject unable to understand the nature, scope and consequences of the study; * participation in any other investigational trial within the past 3 months before enrolment; * planned surgery during the study period; * intention to leave the area of the study site before the end of study period; * any condition which, in the opinion of the investigator, might interfere with the evaluation of the study objective.