The purpose of this study is to, in patients with stable angina pectoris, assess the additional benefit of PCI on top of optimized medical treatment, physical training and smoking cessation with regard to quality of life, achievement of target of treatment and clinical events such as death, acute myocardial infarction, stroke and revascularization.
Patients with stable angina pectoris with a significant coronary stenosis will be randomized to optimized medical treatment, physical training and smoking cessation or to optimized medical treatment, physical training, smoking cessation and complimentary treatment with PCI. All patients will be followed up at six months and at one and five years regarding symptoms, blood lipids, systemic blood pressure, physical training status, smoking habits, and maximal exercise ECG. Achievement of target of treatment will be measured by questions regarding the patients' expectation of the treatment at baseline and at a 6 month follow-up. The questions at 6 months will be based on the interviews at inclusion. Furthermore quality of life will be measured with three different measuring instrument; SF-36 short form, Seattle Angina Questionnaire (SAQ), and EQ-5D. These instruments will be given to the patients at baseline, at six months and at the five year follow up.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
optimized medical treatment, physical training and smoking cessation with complimentary treatment with coronary angioplasty (PCI):
Sahlgrenska University hospital
Gothenburg, Sweden
Quality of life measured by SF36
Time frame: 6 months
Achievement of target of treatment based on interview of the patients
Time frame: 6 months
Death, myocardial infarction, stroke or new revascularization
Time frame: 6 months, one year and five years after randomization
To assess expectations of treatment at inclusion and fulfilment of expectations
Time frame: 6 months
Quality of life measured by EQ5D and Seattle angina questionaire
Time frame: 6 months and 5 years
Health economy
Time frame: 6 months, one year and five years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.