Assessment of Sleep Disturbance in Alzheimer Disease

Centre Hospitalier Universitaire de Nice70 enrolled

Overview

The purpose of this study is to study circadian rhythms, or daily cycles of sleep, wake, and activity. The investigators hope to learn how disturbed sleep in Alzheimer's Disease relates to changes in activity cycles, and how sleep disturbances may affect your daytime alertness. This project selects patients suffering from memory problems, or voluntary to be in our Control Group. There are three parts to this study: Sleep Diaries, Behavioral Questionnaire, and Activity Recordings

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Alzheimer Disease

Interventions

Analysis of sleep disturbanceOTHER

Behavioral Questionnaire Sleep Recordings Genetic analysis

Eligibility

Sex: ALLMin age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * alzheimer disease * MMSE \> 20 * over 65 years old Exclusion Criteria: * new psychotropic drug treatment * patient unable to do neuropsychologic tests

Locations (1)

Centre Mémoire de Ressources et de Recherche, CHU de Nice

Nice, France

Outcomes

Primary Outcomes

assessment of apathy

Time frame: at day 0, just after inclusion

Secondary Outcomes

assessment of sleep disturbance

Time frame: during a week, between day 0 and day 7

determine a genetic relationship between sleep disturbance and alzheimer disease

Time frame: after all genetic analyses of the study

Data from ClinicalTrials.gov

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