The aim of the study is to explore the concept of GnRH-agonist triggering in combination with elective cryopreservation of all 2PN oocytes at larger scale in a pragmatic clinical setting. The question asked is: "Does GnRH-agonist triggering and cryopreservation work", in terms of efficacy and safety, when applied to a larger cohort of patients, and by a number of different centres with different clinical routines.
Study Type
OBSERVATIONAL
Enrollment
51
IVF-Augsburg
Augsburg, Germany
Deutsche Klinik Bad Münder
Bad Münder am Deister, Germany
Department of Obestrics and Gynecology, University Bonn
Bonn, Germany
Cumulative ongoing pregnancy rate (10-12 GWs) per patient within 12 months
Time frame: 12 months after recruitment
ongoing pregnancy rate/frozen-thawed ET
Time frame: 12 months after recruitment
Ongoing pregnancy rate/first frozen-thawed ET
Time frame: 12 months after recruitment
time to pregnancy in weeks
Time frame: 12 months after recruitment
incidence of OHSS III°
Time frame: 12 months after recruitment
number of cumulus-oocyte-complexes
Time frame: 12 months after recruitment
fertilization rate (number COCs/number of 2 PN oocytes
Time frame: 12 months after recruitment
survival rate (number of vital embryos/number of frozen 2 PN oocytes
Time frame: 12 months after recruitment
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Department of Obestrics and Gynecology, University Cologne
Cologne, Germany
Interdisziplinäres Kinderwunschzentrum
Düsseldorf, Germany
University Centre for Reproductive Medicine Franken
Erlangen, Germany
Department of Obestrics and Gynecology, University Clinic of Schleswig-Holstein, Campus Luebeck
Lübeck, Germany
Department of Obestrics and Gynecology, University Magdeburg
Magdeburg, Germany
Kinderwunschpraxis
Tübingen, Germany
Department of Obestrics and Gynecology, University Wuerzburg
Würzburg, Germany