The purpose of this study is to test the success rate of smoking reduction or cessation with different nicotine products.
To test if smoking reduction or cessation is induced with different nicotine products and to investigate the possible health benefits of smoking reduction
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
314
8-12 pieces per day, maximum 24 daily
8-12 pieces per day, maximum 24 daily
6-12 cartridges per day, maximum 12 daily
Smoking Cessation Clinic
Kutná Hora, Czechia
Institute of Hygiene and Epidemiology
Prague, Czechia
Reduction in number of smoked cigarettes/day verified by carbon monoxide (CO) levels
Time frame: Baseline to 6 weeks, 3 and 4 months
Changes in laboratory values of cardiovascular risk factors
Time frame: Baseline up to 12 months
Changes in clinical and laboratory exposure parameters
Time frame: Baseline up to 12 months
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6-12 cartridges per day, maximum 12 daily