Evaluation of the Cardioblate Closure Device in Facilitating Occlusion of the Left Atrial Appendage

Inclusion Criteria: * Subject is greater than or equal to 18 years of age and less than or equal to 80 years of age * Concomitant indication for cardiac surgery for one or more of the following:mitral valve repair or replacement, aortic valve repair or replacement, tricuspid valve repair or replacement, CABG (\>=60 years of age), CABG (\< 60 years of age with a history of atrial fibrillation), surgical ablation or Maze procedure * The subject is willing and able to provide written informed consent and comply with study requirements * The subject is not contra-indicated for intra-operative transesophageal echocardiogram (TEE) Exclusion Criteria: * Thrombus in the LAA and/or left atrium * Prior LAA isolation attempts * Subject is unable to take an anticoagulant during the study follow-up period * Subject is undergoing an emergency cardiac procedure * Life expectancy of less than 12 months * Pregnancy or desire to be pregnant within the 12 months of the study procedure