The purpose of the study is to determine the development of microbial resistance when using one of two topical acne therapies for the treatment of facial acne vulgaris.
To investigate the development of microbial resistance when using one of two topical acne therapies for the treatment of moderate to moderately severe facial acne vulgaris. Clinical efficacy and tolerability will be assessed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
54
Dermatology Specialists, PSC
Louisville, Kentucky, United States
Skin We Care Dermatology
Mason, Ohio, United States
Median Change in Total Propionibacterium Acne (P.Acne) Counts
Median change in total colony forming units of propionibacterium acne (P.acne) will be counted.
Time frame: Baseline, Weeks 2, 4, 8, 12, & 16
Median Change in Clindamycin Resistant P. Acne.
Median change in total colony forming units of clindamycin resistant p. acne.
Time frame: Baseline, Weeks 2, 4, 8, 12, 16
Median Change in Erythromycin-resistant P. Acne Counts
Total colony forming units of erythromycin-resistant p. acnes.
Time frame: Baseline, Weeks 2, 4, 8, 12, and 16
Median Change in Total Acne Lesions
Median Change in Total Acne Lesions
Time frame: Baseline, Weeks 2, 4, 8, 12, and 16
Median Change in Inflammatory Acne Lesion Counts
Median Change in Inflammatory Acne Lesion Counts
Time frame: Baseline, Weeks 2, 4, 8, 12, and 16
Median Change in Noninflammaotry Acne Counts
Median Change in Noninflammaotry Acne Counts
Time frame: Baseline, Weeks 2, 4, 8, 12, and 16
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