* The aim of the study is to compare the effects of coadministration of ezetimibe 10 mg/die + fenofibrate 200 mg/die versus pravastatin 40 mg/die monotherapy in HIV-infected patients treated with protease inhibitors. * Single-centre, open, randomized, controlled, prospective pilot study. * 60 patients will be enrolled in order to reach the target of 50 patients evaluable at the end of the study. The patients will be randomly assigned to a 6-month treatment with ezetimibe+fenofibrate or with pravastatin.The visit will be every month.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
10 mg ezetimibe/day
200 mg fenofibrate/day
40 mg pravastatin/day
Ospedale di Circolo and Fondazione Macchi
Varese, Varese, Italy
RECRUITINGper cent changes of LDL cholesterol, comparison between the 2 treatment regimens
Time frame: After 6 month treatment
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