The purpose of this study is to examine the postprandial (anytime after a meal) effect of different dietary fats on endothelial function in HIV-infected and HIV-uninfected men.
This study requires two visits. Once determined eligible by the study criteria, during the first visit the participant will be randomly placed to receive one of two high-fat meals. The participant will receive the other study meal during the second visit. At each visit, brachial artery ultrasounds will be performed before and 3 hours after the meal is eaten. The sample size is 50 subjects. This study will be conducted at the Clinical Research Center at Tufts Medical Center.
Study Type
OBSERVATIONAL
Enrollment
50
Participant will eat a study meal high in omega-3 fatty acids.
Participant will eat a study meal high in saturated fat.
Tufts University
Boston, Massachusetts, United States
To measure flow-mediated dilation before and after eating the two study meals.
Time frame: Study visit 1 and 2
To compare the effect of different dietary fats on endothelial function.
Time frame: Study visit 1 and 2
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