Plant Stanol Ester Beverage and Ileostoma Patients

University of Helsinki10 enrolled

Overview

We aim to examine efficacy of a plant stanolester beverage to lower serum cholesterol and LDL-cholesterol levels, when given with or without a fatty acid preparation. Study subjects are otherwise healthy proctocolectomized ileostoma patients (n=10), who consume stanolester beverage with or without a fatty acid preparation in a random order for one week period after a standardized low-fat meal. Washout period is 4 weeks. Serum lipids, lipoprotein lipids, sterols and fecal sterols and variables of cholesterol metabolism will be examined accordingly.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Ileostoma

Interventions

Plant stanolester and fatty acidDIETARY_SUPPLEMENT

Plant stanol ester 2gr/day and fatty acid in a beverage compared to plant stanol ester 2gr /day and placebo

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy proctocolectomized subjects with an ileostoma Exclusion Criteria: * Chronic illness

Locations (1)

University of Helsinki, Department of Medicine

Helsinki, Finland

Outcomes

Primary Outcomes

serum cholesterol level

Time frame: After treatment perdiods

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.