Pharmacokinetics and Pharmacodynamics of Nasally Applied Esketamine

University Hospital, Basel, Switzerland

Overview

The purpose of this study is the determination of blood concentration and the effectiveness of esketamine after nasal application.

Study Type

INTERVENTIONAL

Conditions

Pain

Interventions

esketamine hydrochlorideDRUG

Eligibility

Sex: MALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * male * age ≥18 years ≤ 45 years * healthy * non-smoking * BMI 18-27 Exclusion Criteria: * abuse of drugs * known or supposed hypersensitivity and/or contraindication against ketamine or additives * participation of another clinical study within the last 30 days * chronic obstructed nose breathing or nasal polyps * dug allergy * blood donation within the last two months

Locations (1)

Clinical Research Center, University Hospital Basel

Basel, Canton of Basel-City, Switzerland

Data from ClinicalTrials.gov

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