This study is working to evaluate the surgical comprehensive treatment for different types of tumor thrombi in the portal vein for hepatocellular carcinoma patients, to establish a standardized, unified, effective therapeutic program.
Primary liver cancer (PLC) has a great tendency to invade portal vein intravascularly, results in the formation of portal vein tumor thrombus (PVTT), which is a crucial factor that can worsen the prognosis of patients with PLC. In clinical, various treatments have been applied to improve this short-term prognosis, but there was no identical indication for treatment of PLC patients with different PVTT. The objective of this study is to evaluate the surgical comprehensive treatment for different types of tumor thrombi in the portal vein for hepatocellular carcinoma patients, to establish a standardized, unified, effective therapeutic program.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
120
15mg/d×14d
CBP 300mg/d×2d,5-FU 1000mg/d×5d
CBP 300mg/d×2d,5-FU 1000mg/d×5d ,Endostar 15mg/d×14d
Eastern hepatobilliary surgery hospital
Shanghai, Shanghai Municipality, China
overall survival
Time frame: 2010
disease-free survival
Time frame: 1,2 and 3 years
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