Comparison of Anwar and Melles Techniques in Deep Anterior Lamellar Keratoplasty (DALK) for Keratoconus Patients

Shahid Beheshti University of Medical Sciences

Overview

This study will be performed on patients who come to labbafinejad ophthalmic clinic from 20 March 2008. Keratoconus diagnosis will be determined by clinical finding in slit lamp, keratometery and topographic characteristics. Patients will be randomly placed in group A and B. In group A, Anwar surgical method and in B, Melles surgical method, will be done. This is not a blind study due to surgeons' knowledge. All patients will receive Btamethazone drop and Chloramphenicol every 6 hours and will be tapered in two months. In the end anatomical results, complications, BCVA, UCVA, astigmatism, endothelial cell numbers will be compared in two groups by using specular microscopy. Contrast sensivity, central corneal diameter, interface wrinkling and opacity will be measured by metrovison, Confoscan, Photoslit in months 3, 6, 12, respectively and will be evaluated afterwards.

Study Type

INTERVENTIONAL

Conditions

Keratoconus

Interventions

AnwarPROCEDURE

Anwar surgical method

MellesPROCEDURE

Melles surgical method

Eligibility

Sex: ALLMin age: 15 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients with keratoconus * 15\<age\<45 * contact lens intolerance Exclusion Criteria: * Having a history of any other ophthalmic or systemic problem * Central corneal scar * descemet's membrane detachment

Locations (2)

Ophtalmic Research Centre

Tehran, Tehran Province, Iran

Farid Karimian,MD

Tehran, Tehran Province, Iran

Data from ClinicalTrials.gov

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