Effects of Arabinoxylan-Oligosaccharides Compared to Other Prebiotics in Healthy Subjects

KU Leuven20 enrolled

Overview

The purpose of the study is to evaluate the effects of arabinoxylan-oligosaccharides (AXOS) on the colonic metabolism and microbial composition, and to compare these effects with the reference prebiotic fructo-oligosaccharide enriched inulin.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Healthy

Interventions

FOS-INDIETARY_SUPPLEMENT

prebiotic fructo-oligosaccharide enriched inulin intake period: 2 weeks, 1.25 or 2.50g every morning and evening

AXOSDIETARY_SUPPLEMENT

arabinoxylan-oligosaccharides (AXOS) intake period: 2 weeks, 1.25 or 2.50g every morning and evening

Eligibility

Sex: ALLMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy * 18-45 years * regular eating pattern Exclusion Criteria: * gastrointestinal complaints * antibiotic intake * medication influencing gut transit or microbiota * abdominal surgery * pregnancy

Locations (1)

Department of Gastrointestinal Research, Laboratory Digestion and Absorption

Leuven, Leuven, Belgium

Data from ClinicalTrials.gov

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