Comparison of Techniques for Assessing Cardiac Output and Preload in Critically Ill Pediatric Patients

Transonic Systems Inc.7 enrolled

Overview

The ability to measure cardiac output (CO) accurately and reproducibly at frequent intervals remains elusive to the clinician caring for critically ill pediatric patients even though a large proportion of these children are known to have hemodynamic compromise as a result of their illness. Current techniques used in adults to measure CO are not suitable for routine use with pediatric patients. A new ultrasound dilution approach provides an opportunity to measure cardiac output and blood volumes in pediatric patients. The main aim of this study is to compare CO measured by the new method with the clinician's estimate and implied CO from the measurement of the arteriovenous oxygen content difference.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Cardiac Output

Eligibility

Sex: ALLMax age: 16 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with in situ central venous and arterial catheters * Ability to draw blood from arterial and central venous catheters * Presence of parent or guardian to provide consent Exclusion Criteria: * Patients over 16 years of age.

Locations (1)

Golisano Children's Hospital

Rochester, New York, United States

Outcomes

Primary Outcomes

Compare CO measured by the new method with clinician's estimate and implied CO from measurement of arteriovenous oxygen content difference.

Time frame: 5-8 minutes minimum

Secondary Outcomes

Measure blood volumes to compare effects of volume infusion and furosemide.

Time frame: 5-8 minutes minimum