Follow-up Study of Small-intestinal Mucosal Injuries in Chronic Non-steroidal Anti-inflammatory Drugs (NSAIDs)-Users

Inclusion Criteria: * written informed consent * 20 to 85 years of age * RA, OA, or low back pain * taking oral diclofenac sodium over 3 months * No change of drugs before 3 months * under 5 mg of corticosteroid use * CRP \< 1mg/dl Exclusion Criteria: * known or suspected small-bowel disease, including Crohn's disease and seronegative arthritis * prostaglandins, metronidazole or salazosulfapyridine * can not swallow * with pacemaker * after gastrointestinal operation * serious concomitant cardiovascular, endocrine, gastrointestinal(including symptoms of ileus), neurologic, psychiatric, renal, or respiratory disease. * any other conditions that the investigator feels would interfere with data interpretation or create under risk