The Influence of Oral Hygiene on Local Wound and Systemic Infection in Patients With Percutaneous Endoscopic Gastrostomy Placement

Hillel Yaffe Medical Center50 enrolled

Overview

Percutaneous endoscopic gastrostomy (PEG) is commonly used for long term enteral feeding of patients with severe dysphagia. The most common complication is peristomal wound infection. The possible mechanism the bacterial from the oral cavity disseminate during the PEG insertion through the stomach to the abdominal wall, in spite the routine use of antibiotic prophylaxis, have reported low rates of wound infection in patients who were already receiving antibiotics at the time of PEG Our hypothesis that washing the oral cavity with antibiotic solution prior the insertion PEG , We planned a prospective, randomised, double blind, one centre study of antibiotic mouth wash solution (0.2% Chlorhexidine gluconate) as.prophylaxis in PEG

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Dysphagia Peristomal Wound Infection

Interventions

Mouth wash prior to procedure

Plain waterOTHER

Mouth wash prior to procedure

Eligibility

Sex: ALLMin age: 45 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients scheduled to undergo PEG Exclusion Criteria: * Previous GI surgery * Coagulopathy * Sepsis

Outcomes

Primary Outcomes

Assess impact mouth wash (containing 0.2% Chlorhexidine gluconate) (Taro Pharmaceutical Industries Haifa Israel) prior PEG insertion.

Time frame: One month

Secondary Outcomes

Follow the peristomal wound infection in patients who had prepared by mouth wash to a group a patients without mouth washing.

Time frame: One month

Data from ClinicalTrials.gov

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