This study will assess whether coffee consumption: * increases immune responses * decreases inflammatory status
Epidemiological studies suggest that coffee consumption is associated with protective effects against several types of chronic diseases. Recent data have shown that certain coffee components may possess anti-inflammatory and immune-enhancing properties. Low-grade inflammation and poor capacity of immune response is highly prevalent in elderly subjects. The purpose of this study is to evaluate whether coffee consumption improves immune and inflammatory status in healthy elderly subjects. To sort out the role of antioxidants, we will test 2 different soluble coffee, i.e. fully torrefied coffee and partially torrefied coffee.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
116
Fully torrefied coffee
Partially torrefied coffee
INTA University of Chile
Santiago, Santiago Metropolitan, Chile
NK-cell activity
Time frame: will be measured before and after 30 days +/- treatment
Tuberculin test
Time frame: will be measured before and after 30 days +/- treatment
Inflammatory status
Time frame: will be measured before and after 30 days +/- treatment
Gut microbiota profiling
Time frame: will be measured before and after 30 days +/- treatment
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