Study to Assess the Effects of High Protein Diet in Obesity, the LOWER Study

University Medical Center Groningen317 enrolled

Overview

This program is carried out in a dedicated outpatient-clinic in the city of Hengelo for the evaluation and treatment of subjects with obesity. The program puts emphasis on intervention with appropriate diet and physical exercise, and supports the patients in achieving long-term behaviour changes. Interventions which are compared are normal vs high protein/low carb diets.

Assessment focuses on the effect of the specific diets on weight reduction after 3 months, and weight maintenance after 12 months.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

317

Conditions

Obesity

Interventions

Normal protein energy-restrictedDIETARY_SUPPLEMENT

Normal protein diet energy restricted

High protein energy-restrictedDIETARY_SUPPLEMENT

High protein diet, with either low or normal carbohydrate content

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Obesity with BMI \> 27 kg/m2 Exclusion Criteria: * Recent loss of body weight (\>10%) * Underlying malignancy, HIV infection, psychiatric disease * Pregnancy or breast feeding

Locations (1)

Hospital Hengelo

Hengelo, Netherlands

Outcomes

Primary Outcomes

Body weight

Time frame: 1 year

Data from ClinicalTrials.gov

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