Frequency of Metabolic Syndrome in Down Syndrome Patients

Universidad de Guanajuato96 enrolled

Overview

The aim of this study is to assess the frequency of metabolic syndrome in Down syndrome patients because the prevalence of diabetes mellitus and obesity is higher in individuals with Down syndrome than in the general population.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Metabolic Syndrome X Down Syndrome

Eligibility

Sex: ALLMin age: 7 YearsMax age: 24 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of Down syndrome Exclusion Criteria: * History of congenital cardiac defects requiring open-heart surgery * History of gastroenterologic anomalies requiring bowel resection and/or ongoing medical intervention * History of leukemia or other cancer * History of hypothyroidism requiring thyroid hormone replacement

Locations (1)

School of Medicine, University of Guanajuato

León, Guanajuato, Mexico

Outcomes

Primary Outcomes

To asses the frequency of the metabolic syndrome among Down syndrome patients. Metabolic syndrome was defined by Adult Treatment Panel III criteria modified by Halley-Castillo.

Time frame: One year

Secondary Outcomes

Evaluate the insulin resistance and insulin sensitivity using the HOMA and QUICKY methods.

Time frame: One year

Data from ClinicalTrials.gov

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