Cutaneous DNA Damage Caused by UV-A Irradiation

Inclusion Criteria: * Male, * Between 18 and 35 years old, * Healthy volunteers, * Cutaneous phototype 2 or 4 according to the Fitzpatrick classification, * Affiliation to the French Social Security. Exclusion Criteria: * History of photosensibility, * Active smoking or stopped since less than one year, * Dermatological pathology or treatment contra-indicating cutaneous irradiation and skin biopsies, * Any chronic pathology susceptible to interfere with the evaluations related to the protocol, * Allergy to local anaesthetics, * Volunteers who take drugs and/or food complements acting on oxidative stress in the 8 weeks preceding inclusion, * Volunteers who have take paracetamol or aspirin within 7 days prior to the inclusion visit, * Subject in exclusion period for another biomedical research study, * Subject having exceeded the threshold of annual compensation for biomedical research.