Biopsy Incisional With Trepan in Periocular Lesions

University of Sao Paulo40 enrolled

Overview

The purpose of this study was to identify accuracy rates of 2mm punch biopsy technique in diagnosing periocular malignancy.

In each case, the histology obtained at biopsy was compared with that identified at the time of tumor excision.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Tumor

Interventions

Punch BiopsyPROCEDURE

1. Instillation of anesthetic eye drops. 2. Asepsis 3. Placement of surgical cloths and drapes 4. Infiltration of the involved region with anesthetic solution plus adrenalin in1:200.00 dilution. 5. Trephination of the most typical area of the lesion with a punch (2mm in diameter) of stainless steel by applying gentle pressure and twisting the trephine until its introduction into the suspicious lesions 6. Removal of the excised tissue with the aid of an insulin needle or conjuntival forceps, the base then bein cut with an number 11 surgical blade

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * All lesions were initially examined at the slitlamp, after which lesions with malignant characteristics such as texture, size or color alterations asociated with ulceration, prominent borders or elevated contours, irregular borders, telangiectasias or loss of eyelashes were included. Exclusion Criteria: * Lesions with not malignant characteristics

Outcomes

Primary Outcomes

accuracy, positive predictive value, negative predictive value, sensitivity, specificity

Time frame: In each case, the histology obtained at biopsy was compared with that identified at the time of tumor excision.

Data from ClinicalTrials.gov

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