Efficacy and Adverse Effect of Simvastatin Compare to Rosuvastatin in Systemic Lupus Erythematosus (SLE) Patients With Corticosteroid Therapy and High Low-Density Lipoprotein (LDL) Cholesterol Level

Inclusion Criteria: * SLE patients that on prednisolone more than 30 mg/day * Normal liver faction: AST and ALT \< 80 mg/dl * Normal muscle enzyme : CPK \< 100 U/L * LDL cholesterol level \> 100 mg/dl Exclusion Criteria: * Patients that was treated with pulse methylprednisolone or corticosteroid equivalent to prednisolone \> 1mg/kg/day at screening. * Statin allergy * On statin treatment before screening * On cyclosporine, antifugal (azole group), antibiotics (macrolide group), rifampicin, warfarin, phenytoin * Pregnancy * Abnormal liver function: AST or ALT \> 80 mg/dl * Abnormal muscle enzyme : CPK \> 300 U/L