Study of a Parenterally Administered H5N1 Influenza Vaccine in Healthy Adults

Inclusion Criteria: * Healthy volunteers (as concluded from the medical history, physical examination, and clinical judgment) aged 19 to 50 years old * Females using a reliable method of contraception (from 4 weeks prior to the first vaccination until 4 weeks after the second vaccination) and a negative urine pregnancy test will be required before administration of each dose of vaccine * Signed informed consent * Subjects able to understand and comply with the study protocol and complete the Adverse Event Form * Subjects able to attend the scheduled visits * Subjects with normal pre-screening values. If a subjects prescreening samples lie outside the reference values he/she will only be included in the study based upon the medical evaluation of the clinical investigator Exclusion Criteria: * Persons with a history of anaphylaxis or serious reactions to any vaccine * Persons with known hypersensitivity to any of the vaccine components * Persons who have had a temperature \>38oC during the previous 72 hours * Persons who have had an acute respiratory infection during the last 7 days * Women who are pregnant or breast-feeding * Persons with chronic illness at any stage that could interfere with trial conduct or compliance * Persons who have received blood products or immunoglobulins parenterally during the previous 3 months * Persons who have been vaccinated with any vaccine during the 4 weeks preceding the first trial vaccination * Persons with known or suspected immunosuppressive disease or who use systemic immunosuppressive drugs * Persons taking immunostimulant therapy * Persons involved in another clinical trial during the last month. * Suspected non-compliance