Study of Biomarkers of Airway Inflammation (0000-128)

Inclusion Criteria: * Female subjects who can have children must have a negative pregnancy test at screening and agree to use two methods of birth control throughout the study * Male subjects with female partner(s) who can have children agree to use an acceptable method of birth control throughout the study * Subject is a nonsmoker * Subject is in generally good health * Subject is willing to comply with the diet, alcohol, and caffeine study restrictions Exclusion Criteria: * Subject is a nursing mother * Subject has taken oral corticosteroids within 8 weeks or inhaled/nasal corticosteroids within 4 weeks of screening * Subject has nasal polyps, recent nasal surgery, or an ongoing upper or lower respiratory tract infection * Subject has a recent history of allergic rhinitis at screening * Subject has any respiratory disease at screening * Subject has daily phlegm or a chronic cough * Subject is unable to refrain from the use of any prescription or non-prescription drugs or herbal remedies during the study * Subject consumes excessive amounts of alcohol or caffeine * Subject has had major surgery, or donated or lost 1 unit of blood within 4 weeks of screening * Subject has a history of stroke, seizures, or major neurological disorders * Subject regularly uses illicit drugs or has a history of drug/alcohol abuse * Subject received a vaccination within 3 weeks of screening