The purpose of this study is to examine the effect of diet-induced weight loss on the levels of circulating nutrients and hormones which are involved in feelings of hunger and satiety.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
50
Meal replacement, three times daily for 8 weeks
Heidelberg Repatriation Hospital
Melbourne, Victoria, Australia
Difference in fasting and/or post-prandial hormone levels following weight loss and after weight maintenance compared with baseline
Time frame: 2, 6 and 12 months
Difference in fasting and/or post-prandial hormone levels in ketotic compared with non-ketotic state
Time frame: week 8 vs week 10
Correlation of fasting and post-prandial hormone levels with ratings of hunger and satiety
Time frame: 0, 2, 6 and 12 months
Association of psychosocial factors with successful weight maintenance
Time frame: 12 months
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