Eye Movement Recordings in the Diagnosis of Traumatic Brain Injury

VA Office of Research and Development26 enrolled

Overview

The study investigates whether the use of eye movement recordings can provide a reliable diagnostic of previously undiagnosed mild traumatic brain injury (blast and impact) in Operations Enduring Freedom or Iraqi Freedom (OIF/OEF) veterans.

Eye movements are recorded for Operations Enduring Freedom or Iraqi Freedom (OIF/OEF) veterans with mild traumatic brain injury (mTBI) and compared to the eye movements of those without mTBI. By analyzing and characterizing the differences between the two groups, a diagnostic measure of mTBI through the use of eye movements can be developed.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Traumatic Brain Injury

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * OIF/OEF Veteran; * Neuropsych diagnosis of MTBI Exclusion Criteria: * chronically abusing alcohol or illicit drugs. * uncorrected vision prevents subject from effectively viewing the stimuli, unless they can wear contact lenses during the recording session. * inability to make normal eye movements (i.e.: saccades, smooth pursuit) required by study paradigms. Note: Deficit can be caused by taking medications that can potentially affect eye movements or any neurological condition that can interfere with making normal eye movement. * psychological or psychiatric conditions that preclude sustained concentration or ability to perform the tasks.

Locations (1)

Louis Stokes VA Medical Center, Cleveland, OH

Cleveland, Ohio, United States

Outcomes

Primary Outcomes

Stability of Fixation

The ability to keep eye position fixed on a visual target, measured by the distance between the target and eye fixation point averaged over 20 sec.

Time frame: During eye movement recording session (20 sec).

Data from ClinicalTrials.gov

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