Review of Molecular Profiling-Real Time Polymerase Chain Reaction (Rt-Pcr) in Unknown Primary Cancer

SCRI Development Innovations, LLC30 enrolled

Overview

This will be a retrospective review of 30 patients with unknown primary cancer who have had commercially available RT-PCR assays performed on biopsied tumors, in order to determine if the assay results are consistent with clinical features and useful for planning initial therapy or changing therapy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Unknown Primary Cancer

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with RT-PCR testing completed since commercialization of the RT-PCR assay in 2007.

Locations (1)

Tennessee Oncology, PLLC

Nashville, Tennessee, United States

Outcomes

Primary Outcomes

To correlate the tissue of origin predicted by the RT-PCR assay with clinical and pathologic features of patients with carcinoma of unknown primary site.

Time frame: 6 months

Secondary Outcomes

To correlate the tissue of origin predicted by the RT-PCR with actual primary sites found subsequently in a subset of patients.

Time frame: 6 months

To evaluate the utility of RT-PCR assay results in guiding treatment selection in patients with carcinoma of unknown primary site.

Time frame: 6 months

Data from ClinicalTrials.gov

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