Prize Reinforcement Contingency Management for Cocaine Dependence: a 24-week Randomized Controlled Trial

University Hospital, Basel, Switzerland60 enrolled

Overview

The purpose of this study is to determine whether prize-based contingency management (prizeCM) combined with cognitive behavioral therapy (CBT) is more effective in the treatment of of cocaine-dependent patients compared to CBT only. Patients were randomized to prizeCM + CBT (experimental group) or to CBT (control group) an treated over 24 weeks. It is the first trial of this type in Europe.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Cocaine-related Disorders

Interventions

Cognitive behavioral therapy (CBT)BEHAVIORAL

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * cocaine dependence, aged 18 or older, other dependences Exclusion Criteria: * severe somatic, brain, or psychiatric disease, attention deficit disorders with medication methylphenidate

Locations (2)

Universitäre Psychiatrischen Kliniken

Basel, Switzerland

Fondation Phenix

Geneva, Switzerland

Outcomes

Primary Outcomes

retention in treatment, cocaine abstinence

cocaine abstinence: at least 3 consecutive weeks of cocaine abstinence, the maximum number of weeks of continous abstinence and proportions of cocaine-free urine samples during the entire 24-week and at 6-month follow-up.

Time frame: 24 weeks

Secondary Outcomes

patients' satisfaction with the therapy, clinical measures

patients' satisfaction with prize-based contingency management and with CBT

Time frame: 24 weeks

Data from ClinicalTrials.gov

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