Consolidation PET-based and Donor-based After Salvage Therapy in Patients With HL in Relapse or Refractory

Inclusion Criteria: * Patients confirmed Hodgkin's lymphoma at refractory at first line therapy, relapse early or late; * Age \> 18 years; * Life expectancy \> 3 months; * Cardiac, pulmonary, renal and liver functions with normal range; * Written informed consent. Exclusion Criteria: * Any psychological, familiar or geographical conditions that could potentially hinder the compliance to the protocol; * renal failure as creatinine\> 1.2 mg/dl or creatinine clearance \<60 ml/min; * AST/ALT or bilirubin\> 2.5 times the norm; * HCV positivity with signs of ongoing viral replication (HCV PCR + AST\>1.5-2x normal); * Heart disease clinically significant: eg. severe hypertension not controlled, multifocal uncontrolled cardiac arrhythmias, symptomatic ischemic heart disease or congestive heart failure class NYHA class III-IV (Annex 2), previous acute myocardial infarction; * Ventricular ejection fraction \<45%; * decompensated diabetes mellitus not controlled by insulin therapy; Disease with significant pulmonary function defined as FEV1 \<65% of predicted or DLCO \<50% of predicted value; * HIV positive patients; * Patients with uncontrolled infection; * Neoplasia in the last 3 years except carcinoma in situ uterus, neck and basal skin cancer or prostate cancer in early stage localized exeresi treated with surgery or brachytherapy with curative intent, a good prognosis DCIS breast treated with surgery alone; * Drug addiction or alcoholism.