Trial to Determine the Maximum Tolerated Dose of Genexol-PM Plus Gemcitabine and Evaluate Efficacy and Safety of Genexol-PM Regimens in Subjects With Advanced Pancreatic Cancer

Inclusion Criteria: 1. Subjects who aged 18 years or older 2. Subjects whose written informed consent was obtained complying with the local regulatory requirements prior to their participation in the trial 3. Subjects who have histologically or cytologically confirmed unresectable or metastatic epithelial cancer of the exocrine pancreas. High-quality contrast-enhanced CT scanning is required to evaluate resectability. Measurable disease is not required. 4. Subjects with no other malignancy diagnosed within past five years except for: * Cured non-melanoma skin cancer * Cured cervical intraepithelial neoplasia (CIN) * Cured In-situ cervical cancer (CIS) 5. Subjects who are ECOG performance status of ≤ 1