Exercise Following Autologous Peripheral Blood Stem Cell Transplantation

Charite University, Berlin, Germany60 enrolled

Overview

The study evaluates the effects of a supervised exercise program on the physical performance, the mood and the complications of therapy in patients undergoing a high-dose chemotherapy followed by an autologous peripheral blood stem cell transplantation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Enrollment

Conditions

Hematological Disease

Interventions

Supervised exerciseOTHER

The patients will carry out a daily endurance exercise program consisting of walking on a treadmill for 30 minutes at an intensity of about 80% of the maximum heart rate under supervision from study personnel.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-70 * Hematological disease * Treatment with high-dose chemotherapy followed by autologous stem cell transplantation * Understanding of written German Exclusion Criteria: * Cardiorespiratory, metabolical, osteoarticular or immunological diseases which can be aggravated by exercise * Pathological stress-ECG at admission

Locations (1)

Section Sports Medicine, Charité Universitätsmedizin Berlin, Hindenburgdamm 30

Berlin, State of Berlin, Germany

RECRUITING

Outcomes

Primary Outcomes

VO2max

Time frame: At recruitment and after 3 weeks

Secondary Outcomes

Mood

Time frame: At recruitment and after 3 weeks

Duration of aplasia

Time frame: 3 weeks

Complications during hospitalization

Time frame: 3 weeks

Need for transfusion of platelets and red blood cells

Time frame: 3 weeks

Central Contacts

Fernando Dimeo, MD

CONTACT

+493084452098 fernando.dimeo@charite.de

Data from ClinicalTrials.gov

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