Cloxacillin as Prevention of Double Lumen Infection in Hemodialysis Patients

Shiraz University of Medical Sciences100 enrolled

Overview

The purpose of this study is to investigate whether cloxacillin lock is effective in prevention of double lumen infection.

Double lumen infection is one of the causes of morbidity and mortality in hemodialysis patients. Many strategies used to prevent it and one of them is antibiotic lock. Thus we select chronic hemodialysis patients and divided them into 2 groups. One group received cloxacillin and heparin as catheter lock and the second group received only heparin lock.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

100

Conditions

Double Lumen Infection Hemodialysis

Interventions

cloxacillinDRUG

cloxacillin 100mg/ml as catheter lock at the end of hemodialysis

heparinDRUG

heparin 1000iu/ml as catheter lock at the end of hemodialysis

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * hemodialysis for 3 months * at least 2 time dialysis/week Exclusion Criteria: * active infection * acute renal failure

Locations (1)

Shiraz University Hemodialysis Center

Shiraz, Fars, Iran

Outcomes

Primary Outcomes

catheter infection

Time frame: 6 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.