The Comparison of Efficacy for Cervical Ripening in Labor Induction Between Titrated and Conventional Oral Misoprostol

Inclusion Criteria: * age 18 years old or more * singleton pregnancy at 37 weeks gestation or more * cephalic presentation * reassuring fetal heart rate pattern * admission for labor induction due to medical or obstetrical conditions * bishop score less than 6 * giving consent and having signed the consent form for this study Exclusion Criteria: * parity more than 3 * estimated fetal weight more than 3,500 grams * non-reassuring fetal heart rate pattern * having contraindication for vaginal delivery * previous uterine scar * suspected abruptio placenta with non-reassuring fetal heart rate pattern * abnormal bleeding per vagina, except bloody show * PROM * having underlying cardiac, hepatic, or renal diseases * having history of allergy to misoprostol or prostaglandin analogues * cervical dilatation 3 centimeters or more * uterine contraction 3 times or more in 10 minute