The purpose of this study is to evaluate the yield of endoscopic guided fine needle aspirations (by means of transoesophageal endoscopic ultrasound : EUS-FNA or transbronchial endoscopic ultrasound : EBUS-TBNA) in patients with a clinical suspicion for sarcoidosis stage I-II; but in whom the preceding bronchoscopy did not result in a qualifying diagnosis.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
100
Bronchoscopy, only if no diagnosis is obtained, patients go for EUS-FNA or EBUS-TBNA, only if no diagnosis is obtained, patients go for surgical biopsy
OLV Ziekenhuis Aalst
Aalst, Belgium
Universitair Ziekenhuis Antwerpen
Antwerp, Belgium
ZNA Antwerpen
Antwerp, Belgium
The diagnostic yield of state-of-the art bronchoscopy (including TBB, EBB and TBNA)
Time frame: At the end of study
The role of endosonography (EUS-FNA or EBUS-TBNA) in demonstrating non-caseating granulomas after a non-qualifying bronchoscopy
Time frame: At the end of study
Prevalence of sarcoidosis and alternate diagnosis
Time frame: At the end of study
Stage distribution
Time frame: At the end of study
Complication rate of each type of procedure
Time frame: At the end of study
Cost to obtain a qualifying diagnosis with this strategy in this population
Time frame: At the end of study
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AZ St. Jan Hospitaal Brugge
Bruges, Belgium
Cliniques Universitaires St. Luc
Brussels, Belgium
Höpital Erasme Brussel
Brussels, Belgium
University Hospital Brussels
Brussels, Belgium
CHU Charleroi
Charleroi, Belgium
University Hospital Ghent
Ghent, Belgium
Virga Jesse Hospitaal
Hasselt, Belgium
...and 5 more locations