CopiOs® Pericardium Membrane for Localized Alveolar Ridge Augmentation

Inclusion Criteria: * Male or female, of any ethnicity, between 18 and 99 years of age * Health status of P1(ASA I) or P2 (ASA II), as classified by the American Academy of Anesthesiologists * Able to communicate with the investigator and read, understand, and sign the informed consent form * No evidence of active moderate or severe periodontitis * Must be available for multiple follow-up visits for the duration of the study * The study site must exhibit a partially edentulous ridge of the maxilla or mandible with at least one tooth-span in length and less than 5.5 mm in its smallest buccolingual dimension as measured by ridge-mapping calipers (#RIDGE-CALIPER, Salvin Dental Specialties, Inc., Charlotte, NC). Exclusion Criteria: * Inability or failure to maintain adequate oral hygiene * Women who are bread-feeding, pregnant, or who intend to become pregnant during this study period. Women of childbearing potential should be practicing a medically accepted method of birth control * Patients with unstable systemic diseases * Patients with compromised immune system (e.g. uncontrolled diabetes, etc.) or unstable bleeding disorder * Patients with active infectious diseases (e.g. hepatitis, tuberculosis, HEV, etc.) * Patients with a mental disability that may hinder participation in the study (e.g. inability to follow through with oral hygiene instructions, postoperative instructions, follow-up commitments, etc.) * Patients taking steroid medications or undergoing other immunosuppressive therapy * Radiation, cancer therapy, and/or radiation specifically at the oral cavity within the last 6 months * History of previous ridge augmentation at the site of interest * Augmentation sites with localized pathology * Patient who has participated in a clinical trial within 30 days of being enrolled in this study, is currently enrolled in another study, or plans to enroll in another study before the completion of of this study. * Unresolved oral pathologies (e.g. periodontal disease, caries, etc.) * Medications or conditions contraindicated for bone regeneration: methotrexate, corticosteroids, history of bisphosphonate use, cyclosporine-A, etc. * Patients who have more than a minimal tobacco use (e.g. \>10 cigarettes per day) * Other conditions the investigator may feel would inhibit the patient from being a good candidate for this study or which are contraindicated in the Directions for Use. * Note: Careful consideration should be given to alternative therapies prior to performing bone grafting in patients who have severe endocrine-induced bone diseases (e.g.hyperparathyroidism), or who are undergoing current therapy with drugs that intervene in calcium metabolism.