The primary purpose of this study is to evaluate the association between nonalcoholic fatty liver disease (NAFLD) by computed tomography (CT) scan and coronary artery disease (CAD) measured by the calcium (CAC) score among HIV-infected persons.
Study Type
OBSERVATIONAL
Enrollment
233
Naval Medical Center San Diego (NMCSD)
San Diego, California, United States
Coronary artery disease (CAD) measured by the CAC score
Time frame: 1 year
To determine the prevalence of coronary artery disease as determined by computed tomography (CT) of the coronary arteries among HIV patients, and to compare it to data from the general population using normative data from recent publications
Time frame: 1 year
To evaluate predictors for coronary artery disease including demographics, concurrent conditions (e.g., diabetes, hyperlipidemia, tobacco use), and HIV factors such as ARV duration, HIV duration, and lipodystrophy
Time frame: 1 year
To investigate the relationship between inflammatory markers (CRP, ESR), d-dimer, adiponectin levels, future inflammatory markers, and genetic polymorphisms with the presence of coronary disease and NAFLD
Time frame: 1 year
To assess the relationship between increased pericardial fat on CT scan with visceral fat and cardiovascular disease
Time frame: 1 year
To determine if Hounsfield units taken in the heart and aorta estimates hemoglobin levels
Time frame: 1 year
To measure the pulmonary artery size to evaluate for prevalence of asymptomatic pulmonary hypertension among HIV-infected persons
Time frame: 1 year
To describe the outcome of a positive CAC score in terms of follow-up test/procedure results to help describe the clinical significance of elevated scores.
Time frame: 1 year
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