Ondansetron for the Treatment of Heavy Drinking Among Emerging Adults

Inclusion Criteria: * White Males and females who have given written informed consent. * Ages 18 through 25;also, patients must weigh ≥40 kg and ≤140 kg. * Good physical health as determined by a complete physical examination, an EKG within normal limits, and laboratory screening tests within acceptable parameters. * At least an average of one episode of binge or heavy drinking per week in the past month prior to enrollment. For men and women, that is ≥5 and ≥4 drinks/drinking day, respectively.They also need to report at least one day of heavy drinking within the 7 days prior to randomization. * The pregnancy test for females at intake must be negative. Additionally, women of childbearing potential must be using an acceptable form of contraception. * Literate in English and able to read, understand, and complete the rating scales and questionnaires accurately, follow instructions, and make use of the behavioral treatments. * Answer an advertisement in the newspaper/radio/television, and express a wish to stop heavy drinking. * Willingness to participate in behavioral treatments to stop heavy drinking Exclusion Criteria: Please contact site for additional information