Efficacy and Safety Study of Second-Line Treatment for Hypertension With Autosomal Dominant Polycystic Kidney Disease(ADPKD)

Inclusion Criteria: * ADPKD patients * Blood pressure measured at out-patient setting is above 120/80 mmHg * Age between 20 and 60 years old * eGFR more than 30 ml/min/1.73m2 * Patients give informed consent Exclusion Criteria: * Patients with severe cardiovascular and hepatic disorders * Patients with complications of central nervous vascular disorders * Women who are breast feeding and females of childbearing potential who are not using acceptable contraceptive methods * Patients currently engaging in other experimental protocol * Patients with intracranial aneurysma * Patients who must use diuretics * Allergic patients to Candesartan or Cilnidipine * Patients whose hypertension is not controlled by medication of this protocol