Viral Triggers in Pediatric Lung Transplantation

National Institute of Allergy and Infectious Diseases (NIAID)61 enrolled

Overview

The purpose of this study is to determine whether respiratory viral infections increase the risk of bronchiolitis obliterans syndrome (BOS), obliterative bronchiolitis (OB), death, or retransplantation in children who have received lung transplants.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Lung Transplant Bronchiolitis Obliterans Obliterative Bronchiolitis

Eligibility

Sex: ALLMax age: 21 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Parent or legal guardian willing and able to provide informed consent * Participant of first single or bilateral heart-lung transplant Exclusion Criteria: * Recipient of multi-organ transplant (aside from heart-lung) * Condition or characteristic which in the opinion of the investigator makes the participant unlikely to complete the study

Locations (6)

Stanford University

Palo Alto, California, United States

Children's Hospital Boston

Boston, Massachusetts, United States

Washington University

St Louis, Missouri, United States

Nationwide Children's Hospital

Columbus, Ohio, United States

Outcomes

Primary Outcomes

The earliest time to BOS or OB, retransplantation or death

Time frame: Within 24 months of transplant

Secondary Outcomes

Time to each of the following events: BOS or OB, retransplantation or death

Time frame: Within 24 months of transplant

Data from ClinicalTrials.gov

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