Augmentation of Screening Colonoscopy With Fecal Immunochemical Testing

Inclusion Criteria: Group I (positive colonoscopy) * 18 to 75 years of age * male or female * willing to provide written informed consent * In the event that the colonoscopy is incomplete, or polypectomy is partial, the above patients are eligible if a successful examination is completed within 6 months of the inadequate exam. Group II (negative colonoscopy) * 50 to 69 years of age * Male or female * Willing to provide written informed consent * In the event that the colonoscopy is incomplete, the patient is eligible if a successful examination is completed within 6 months of the inadequate exam. Exclusion Criteria: Group I (positive colonoscopy) * chronic use of coumadin * history of previous GI malignancy, inflammatory bowel disease (Crohns disease, ulcerative colitis) * age or health status contraindicates repeat colonoscopy * history of Familial Polyposis or Hereditary Nonpolyposis Colon Cancer Syndrome * The index colonoscopy resulted in a perforation requiring surgical repair * An otherwise qualifying colonoscopy is followed by a recommendation for repeat colonoscopy in ≤ 1 yr. Group II (negative colonoscopy) * chronic use of coumadin * history of previous GI malignancy, inflammatory bowel disease (Crohns disease, ulcerative colitis) * age or health status contraindicates repeat colonoscopy * history of Familial Polyposis or Hereditary Nonpolyposis Colon Cancer Syndrome * The index colonoscopy resulted in a perforation requiring surgical repair * Significant family history resulting in a recommendation for repeat colonoscopy in 5 years or less