Effect of Moxifloxacin Versus Gatifloxacin on Corneal Epithelium Following Pterygium Excision

Meir Medical Center40 enrolled

Overview

The purpose of this study is to determine whether there is a difference in corneal epithelial healing rate and/or toxicity following pterygium excision, between eyes treated post-operatively by moxifloxacin(VIGAMOX)versus gatifloxacin (ZYMAR).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Primary Pterygium

Interventions

Moxifloxacin ophthalmic solution 0.5% ; Gatifloxacin ophthalmic solution 0.3%DRUG

Each drug will be given 4 times a day, 1 drop each time to the operated eye, for 21 days.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. diagnosis of primary pterygium with a clinical indication for surgery 2. informed consent Exclusion Criteria: 1. known allergic reaction to fluoroquinolones. 2. secondary\\recurrent pterygium or clinical suspected conjunctival tumor. 3. eye surgery in the last 6 months. 4. eye disorders: severe dry eye syndrome, ocular surface diseases, glaucoma, recurrent corneal erosions, chronic corneal diseases, after chemical burn. 5. low compliance. 6. pregnancy