The Effect of Sildenafil on Sleep-Disordered Breathing in Obese Patients With Sexual Dysfunction

Assaf-Harofeh Medical Center50 enrolled

Overview

Sildenafil has been shown to aggravate sleep-disordered breathing in patients with severe obstructive sleep apnea. The aim of the present study is to examine the frequency of sleep-disordered breathing in obese patients who are candidates for treatment with sildenafil for sexual dysfunction. In addition we wish to assess the effect of sildenafil on sleep-disordered breathing.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sildenafil Sleep Apnea Sexual Dysfunction Obesity

Eligibility

Sex: MALEMin age: 40 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age - 40-65 years * BMI equal to or over 30 Exclusion Criteria: * A known cardiorespiratory, liver or kidney disease * Treatment with nitrates or alfa blockers * Performed polysomnography in the past

Locations (1)

Asaf Harofeh Medical Center

Ẕerifin, Israel

RECRUITING

Outcomes

Primary Outcomes

apnea hypopnea index after sildenafil vs. placebo

Time frame: Hours

Secondary Outcomes

Sleep parameters (latency, efficiency etc) following sildenafil vs. placebo

Time frame: hours

Central Contacts

Isaac Shpiree, MD

CONTACT

972-8-9779024 I_shpirer@yahoo.com

Arnon Elizur, MD

CONTACT

972-8-9779817 elizura@gmail.com

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.