Advances in critical care medicine have dramatically improved the survival of critically ill patients requiring prolonged mechanical ventilation. However, there are no systematic follow-up, rehabilitation, or psychoeducational interventions for these vulnerable patients or their family caregivers who contribute to survivor recovery and rehabilitation. Major barriers to developing these programs for survivors of prolonged mechanical ventilation and their caregivers include the following: 1. There is inadequate information about the determinants of long-term functional outcomes for a diverse group of survivors of prolonged mechanical ventilation. 2. There is inadequate information about the needs of survivors of prolonged mechanical ventilation and their family caregivers across the trajectory of illness (i.e., from the ICU to the community). 3. There is a poor understanding of the development of ICU-acquired muscle injury. Towards RECOVER is the very first study to identify survivors of prolonged mechanical ventilation who are at-risk for poor functional outcomes, to identify elements of the care-giving situation that put caregivers at risk for poor quality of life and mental health, to catalogue the rehabilitative needs of patients and family caregivers across the illness trajectory, and to evaluate the mechanism of critical illness associated muscle injury. The RECOVER Program consists of Four Phases: * Phase I: Towards RECOVER * Phase II: RECOVER development and pilot testing * Phase III: RECOVER randomized controlled trial * Phase IV: Long-term implementation of RECOVER
Study Type
OBSERVATIONAL
Enrollment
500
Sunnybrook
Toronto, Ontario, Canada
RECRUITINGSt. Michael's Hospital
Toronto, Ontario, Canada
RECRUITINGMount Sinai Hospital
Toronto, Ontario, Canada
RECRUITINGToronto Western Hospital
Toronto, Ontario, Canada
RECRUITINGToronto General Hospital
Toronto, Ontario, Canada
RECRUITINGFunctional Independence Measure (FIM) - ICU Survivor
Time frame: 7 days, 3 months, 6 months, 12 months and 24 months post-ICU discharge
Six Minute Walking Test (6MWT) - ICU Survivor
Time frame: 7 days, 3 months, 6 months, 12 months and 24 months post-ICU discharge
Medical Outcomes Study Short Form -36 Questionnaire (SF-36) - ICU Survivor
Time frame: 3 months, 6 months, 12 months and 24 months post-ICU discharge
Beck Depression Inventory-II (BDI-II) - ICU Survivor
Time frame: 3 months, 6 months, 12 months and 24 months post-ICU discharge
Impact of Event Scale (IES) - ICU Survivor
Time frame: 3 months, 6 months, 12 months and 24 months post-ICU discharge
Hospital mortality - ICU Survivor
Time frame: 1 and 2 years post-ICU discharge
Pattern and Cost of Post-hospital discharge Healthcare Utilization (Resources/Costs) - ICU Survivor
Time frame: 3 months, 6 months, 12 months and 24 months post-ICU discharge
The Positive Affect Scale (PAS) - Family Caregivers
Time frame: 7 days, 3 months, 6 months, 12 months and 24 months post-ICU discharge
The Centre for Epidemiological Studies Depression Scale (CESD) - Family Caregivers
Time frame: 7 days, 3 months, 6 months, 12 months and 24 months post-ICU discharge
Medical Outcomes Study Short Form -36 Questionnaire (SF-36) - Family Caregivers
Time frame: 7 days, 3 months, 6 months, 12 months and 24 months post-ICU discharge
The Care-giving Impact Scale (CIS) - Family Caregivers
Time frame: 7 days, 3 months, 6 months, 12 months and 24 months post-ICU discharge
The Care-giving Assistance Scale (CAS) - Family Caregivers
Time frame: 7 days, 3 months, 6 months, 12 months and 24 months post-ICU discharge
The 4-item Personal Gain Scale & Pearlin's Mastery Scale - Family Caregivers
Time frame: 7 days, 3 months, 6 months, 12 months and 24 months post-ICU discharge
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