The main objective of the study is to analyze the influence of several environmental (i.e., timing: seasonal, circadian) and demographic conditions (i.e., age, gender, menstrual cycle) on anesthetic drug requirements (hypnotic and opiate).
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
3,278
Propofol and Remifentanil are administered automatically using a closed-loop system
CHU Besançon
Besançon, France
Centre Hospitalier de Dreux
Dreux, France
Hôpital Tenon
Paris, France
Hôpital Foch
Suresnes, France
The dose of propofol required to maintain BIS (bispectral index) between 40 and 60 during maintenance of anesthesia
Time frame: during anesthesia
Propofol dose required for anesthesia induction
Time frame: intraoperative period
Remifentanil dose required for anesthesia induction
Time frame: intraoperative period
Remifentanil dose requirements for maintenance of anesthesia
Time frame: intraoperative period
Wake up time
Time frame: intraoperative period
Explicit memorisation
Time frame: post-operative period
Propofol and remifentanil requirements according to the surgical technique
Time frame: post-operative period
Analysis of subgroup of patients according to their clinical status
analysis of subgroup of patients according to their clinical status (eg: age)
Time frame: post-operative period
Analysis of subgroup of patients according to the surgical approach
analysis of subgroup of patients according to the surgical approach ("open" surgery versus "minimal invasive" surgery)
Time frame: post-operative period
Analysis of subgroup of patients according to their pathology
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analysis of subgroup of patients according to their pathology (eg: burns)
Time frame: post-operative period