Effect of Myoma Removal on Blood Pressure and Erythropoetin Level

Shiraz University of Medical Sciences28 enrolled

Overview

The effect of myoma removal was studied on 28 patients with hypertension and myoma by holter monitoring and erythropoetin level check.

Background: Myoma is the most common gynecoid tumor and produces many vasoactive substances, which may be a cause for secondary hypertension. Early reports suggested the association of myoma and hypertension. We studied the effect of myoma removal on hypertension and erythropoietin level to evaluate this hypothesis. Patients \& Methods: In this single centered prospective cohort study, in twenty eight patients who were candidates for myomectomy due to myoma, 24 hour holter monitoring of blood pressure and serum erythropoietin were checked before and 6 weeks after hysterectomy.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

QUADRUPLE

Enrollment

Conditions

Myoma Hypertension

Interventions

myoma removalPROCEDURE

surgical removal of myoma by hysterectomy

Eligibility

Sex: FEMALEMin age: 22 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: * candidate for myoma removal by hysterectomy * operable * hysterectomy is indicated Exclusion Criteria: * patient refusal * inoperable patients * other secondary cases of hypertension

Locations (1)

Cardiology Ward Shiraz University of Medical Sciences

Shiraz, Fars, Iran

Outcomes

Primary Outcomes

24 hour holter monitoring of blood pressure

Time frame: 6 weeks

Secondary Outcomes

erythropoetin level

Time frame: 6 weeks

Data from ClinicalTrials.gov

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